Effect of antibiotic therapy with agents with in vitro inhibitory activity against colonizing methicillin-resistant Staphylococcus aureus (MRSA) strains. One patient (A) received oral vancomycin for treatment of Clostridium difficile-associated diarrhea and a second (B) received oral levofloxacin for treatment of a urinary tract infection. The minimum inhibitory concentration (MIC) of vancomycin for the MRSA isolate in A was 0.25 μg/mL; the MIC of levofloxacin for the MRSA isolate in B was 0.125 μg/mL). + = positive nares culture; - = negative nares culture; solid circles = density of MRSA in stool.
Bhalla et al. BMC Infectious Diseases 2007 7:105 doi:10.1186/1471-2334-7-105