Table 2

Efficacy and tolerability of the different drugs used in 415 patients with Mediterranean spotted fever.


Chloramphenicol n = 107
Clarithromycin n = 230
Azithromycin n = 78
p

Mean time to defervescence (h)
40.62
41.94
47.13
0.093
Hospitalization mean (days)
5.4
3.4
4.1
0.018
Prolonged fever / relapse (%)
0
2 (0.9)
9 (11.5)
< 0.01
Side effects requiring drug discontinuation (%)
0
16 (7)
1 (1.3)
< 0.01

Colomba et al. BMC Infectious Diseases 2006 6:60   doi:10.1186/1471-2334-6-60