|
Significant genes with mean fold changes1 of at least ± 2.50 as given by microarray2 |
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| GeneBank identifier |
Gene symbol |
Gene name |
Biological process |
Fold change |
|
|
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| NM_005532 |
IFI27 |
Interferon, alpha-inducible protein 27 |
Immune response |
+13.29 |
| NM_005143 |
HP |
Haptoglobin |
Defence response |
+5.71 |
| NM_006417 |
IFI44 |
Interferon-induced protein 44 |
Immune response |
+4.86 |
| NM_024021 |
MS4A4A |
Membrane-spanning 4-domains, subfamily A, member 4 |
Signal transduction |
+4.42 |
| NM_004994 |
MMP9 |
Matrix metalloproteinase 9 |
Collagen catabolism |
+3.93 |
| BC035682 |
HBZ |
Hemoglobin, zeta |
Oxygen transport |
+3.78 |
| NM_015535 |
DNAPTP6 |
DNA polymerase-transactivated protein 6 |
+3.57 |
|
| NM_000519 |
HBD |
Hemoglobin, delta |
Oxygen transport |
+3.40 |
| NM_005330 |
HBE1 |
Hemoglobin, epsilon 1 |
Oxygen transport |
+3.06 |
| NM_006187 |
OAS3 |
2'-5'-oligoadenylate synthetase 3, 100kDa |
Immune response |
+2.99 |
| NM_000566 |
FCGR1A |
Fc fragment of IgG, high affinity Ia, receptor (CD64) |
Immune response |
+2.88 |
| NM_006949 |
STXBP2 |
Syntaxin binding protein 2 |
Intracellular protein transport |
+2.86 |
| NM_033255 |
EPSTI1 |
Epithelial stromal interaction 1 (breast) |
+2.83 |
|
| NM_002759 |
EIF2AK2 |
Eukaryotic translation initiation factor 2-alpha kinase 2 |
Immune response |
+2.78 |
| NM_016633 |
ERAF |
Erythroid associated factor |
Hemoglobin metabolism |
+2.73 |
| NM_006770 |
MARCO |
Macrophage receptor with collagenous structure |
Response to pathogenic bacteria |
+2.72 |
| NM_001724 |
BPGM |
2,3-bisphosphoglycerate mutase |
Carbohydrate metabolism |
+2.60 |
| NM_000904 |
NQO2 |
NAD(P)H dehydrogenase, quinone 2 |
Electron transport |
+2.56 |
| NM_006820 |
IFI44L |
Interferon-induced protein 44-like |
Immune response |
+2.55 |
| NM_005101 |
G1P2 |
Interferon, alpha-inducible protein (clone IFI-15K) |
Immune response |
+2.54 |
| NM_024572 |
GALNT14 |
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 |
+2.53 |
|
| NM_203339 |
CLU |
Clusterin |
Immune response |
+2.50 |
| NM_005581 |
LU |
Lutheran blood group (Auberger b antigen included) |
Cell adhesion |
-2.55 |
| NM_080819 |
GPR78 |
G protein-coupled receptor 78 |
G-protein coupled receptor protein signaling pathway |
-2.70 |
| NM_000797 |
DRD4 |
Dopamine receptor D4 |
G-protein coupled receptor protein signaling pathway |
-2.89 |
| NM_006249 |
PRB3 |
Proline-rich protein BstNI subfamily 3 |
G-protein coupled receptor protein signaling pathway |
-2.91 |
| NM_021983 |
HLA-DRB4 |
Homo sapiens major histocompatibility complex, class II, DR beta 4 |
Immune response |
-3.31 |
| NM_000558 |
HBA1 |
Hemoglobin alpha 1 |
Oxygen transport |
-4.61 |
| L34088 |
HLA-DQA1 |
Major histocompatibility complex, class II, DQ alpha 1 |
Immune response |
-4.70 |
| NM_001828 |
CLC |
Charcot-Leyden crystal protein |
Antimicrobial humoral response |
-6.08 |
|
1Gene expressions given as mean of the individual fold changes (signal intensity in a case minus signal intensity in the corresponding control). 2Gene expressions as given by microarray in whole blood of five male infants hospitalised with respiratory syncytial virus, subtype B, bronchiolitis versus five one year old male controls exposed to RSV during infancy but not hospitalised and/or treated for bronchiolitis | ||||
Fjaerli et al. BMC Infectious Diseases 2006 6:175 doi:10.1186/1471-2334-6-175 |
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