Table 4 |
||||||||
|
Head-to-head comparison between smear microscopy and phage assays |
||||||||
|
Smear microscopy |
Phage test |
Difference (Phage – Microscopy) |
||||||
|
|
||||||||
|
Study |
Year |
Sample size |
Sensitivity |
Specificity |
Sensitivity |
Specificity |
Sensitivity |
Specificity |
|
|
||||||||
|
Commercial assays |
||||||||
|
Albay |
2003 |
192 |
0.58 (0.44,0.70) |
1.00 (0.97,1.00) |
0.88 (0.77,0.94) |
097 (0.92,0.99) |
0.30 |
- 0.03 |
|
Albert |
2002 |
1618 |
0.62 (0.55,0.69) |
0.97 (0.96, 0.98) |
0.72 (0.66,0.78) |
0.99 (0.98,0.99) |
0.10 |
0.02 |
|
Alcaide |
2003 |
2048 |
0.73 (0.65,0.80) |
0.99 (0.98,0.99) |
0.58 (0.50,0.66) |
0.99 (0.99,0.99) |
-0.15 |
0 |
|
Bellen |
2003 |
204 |
0.89 (0.82,0.95) |
0.60 (0.50,0.70) |
0.31 (0.22,0.41) |
0.86 (0.78, 0.92) |
- 0.58 |
0.26 |
|
Butt |
2004 |
160 |
0.70 (0.57.0.81) |
0.95 (0.89,0.998) |
0.77 (0.64, 0.87) |
0.96 (0.90,0.99) |
0.07 |
0.01 |
|
Marei |
2003 |
38 |
0.64 (0.31,0.89) |
0.93 (0.76, 0.99) |
0.55 (0.23, 0.83) |
1.00 (0.87, 1.00) |
-0.09 |
.07 |
|
Mbulo |
2004 |
496 |
0.45 (0.32, 0.60) |
0.98 (0.91, 1.00) |
0.45 (0.32, 0.60) |
0.91 (0.82, 0.96) |
0 |
-.07 |
|
Muzaffar |
2002 |
514 |
0.71 (0.65,0.77) |
0,94 (0.90,0.96) |
0.82 (0.76,0.86) |
0.98 (0.95,0.99) |
0.11 |
0.05 |
|
|
||||||||
|
In- house assays |
||||||||
|
Mbulo |
2004 |
115 |
0.48 (0.29, 0.60) |
0.90 (0.81, 0.95) |
0.21,(0.08,0.40) |
0.91 (0.82,0.96) |
-0.27 |
0.14 |
|
McNerney |
2004 |
496 |
0.60 (0.53,0.66) |
0.87(0.83,0.91) |
0.44 (0.37, 0.51) |
0.92 (0.89,0.95) |
- 0.16 |
0.05 |
|
|
||||||||
|
Kalantri et al. BMC Infectious Diseases 2005 5:59 doi:10.1186/1471-2334-5-59 |
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