BMC Infectious Diseases

official impact factor 2.83

Open Access Research article

Mutational dynamics of the SARS coronavirus in cell culture and human populations isolated in 2003

Vinsensius B Vega1, Yijun Ruan1, Jianjun Liu1, Wah H Lee1, Chia L Wei1, Su Y Se-Thoe2, Kin F Tang3, Tao Zhang1, Prasanna R Kolatkar1, Eng E Ooi3, Ai E Ling2, Lawrence W Stanton1, Philip M Long4 and Edison T Liu1*

Author Affiliations

1 Genome Institute of Singapore, 60 Biopolis Street, Singapore 138672

2 Virology Section, Department of Pathology, Singapore General Hospital, Singapore

3 Environmental Health Institute, 41 Science Park Road, Singapore Science Park II, Singapore 117610

4 Center for Computational Learning Systems, Columbia University, New York, NY 10027 USA

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BMC Infectious Diseases 2004, 4:32 doi:10.1186/1471-2334-4-32

Published: 6 September 2004

Additional files

Additional File 1:

Table S1 List of the sequences used in the analysis. This list is available at http://giscompute.gis.a-star.edu.sg/sars_mut_dyn/

Format: XLS Size: 24KB Download file

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Additional File 2:

Table S2 Single nucleotide variations (SNVs) detected initially in capillary sequencing (second row) and subsequently confirmed by MALDI-TOF MS-based genotyping (first row). This table is available at http://giscompute.gis.a-star.edu.sg/sars_mut_dyn/

Format: XLS Size: 24KB Download file

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Additional File 3:

Table S3 Complete list of single nucleotide variations (SNVs) observed in the 54 SARS-CoV isolates. The Singapore sequences used were all based on capillary sequencing. This data is available at http://giscompute.gis.a-star.edu.sg/sars_mut_dyn/

Format: XLS Size: 295KB Download file

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Open Data