Table 2

HRHPV Hybrid Capture II performance for the diagnosis of CIN2/3

referral smear
cut off
n
sensitivity
specificity
NPV
NLR
OR

MD & BL
1 RLU
133
97%
37%
97%
0.089
17
MD & BL
3 RLU
133
97%
46%
98%
0.072
26
1xMD
1 RLU
110
97%
36%
97%
0.096
17
1xMD
3 RLU
110
97%
41%
97%
0.083
19
3xBL
1 RLU
23
100%
52%
100%
NA
NA
3xBL
3 RLU
23
100%
64%
100%
NA
NA
MD & BL in woman >30y
1 RLU
66
100%
47%
100%
NA
NA
MD & BL in woman >30y
3 RLU
66
100%
58%
100%
NA
NA

MD = mild dyskaryosis, BL= borderline, NA = non applicable due to 0 in 2 × 2 table

Guyot et al. BMC Infectious Diseases 2003 3:23   doi:10.1186/1471-2334-3-23