Table 2

Mutation frequency in non-HSV DNA.

Virus^a

Mutation Frequency^b (%)

HSV-2 SB5

1.7, 2.0, 1.7^c

HSV-2 SB5PR

2.0, 1.8, 2.1

HSV-2 6652

0.7, 0.9, 1.1

HSV-2 6652PR

1.3, 1.0, 1.5

HSV-2 83D

0.8, 1.1, 1.0

HSV-2 83D PR

1.6, 1.2, 1.8

HSV-2 6757

4.1, 3.4, 4.9

HSV-2 6757PR

1.2, 1.1, 1.1

HSV-1 SC16

2.6, 2.2, 2.1

PAA^r5

3.5, 3.6, 4.1

^aVirus labeled PR represents pol-recombinant virus. ^bMutation frequency = (number of white colonies for test sample/ number of blue colonies for test sample) - (number of white colonies in control sample/number of blue colonies in control sample) × 100. ^cThree independent experiments were performed, with data presented from experiment 1, 2 and 3, respectively.

Duffy et al. BMC Infectious Diseases 2002 2:7   doi:10.1186/1471-2334-2-7