Table 1

Characteristics of 16 patients with definite Lyme arthritis and 5 patients with probable Lyme arthritis
Definite
Age (years) Gender History of prior tick bite History of prior EM Duration of arthritis (weeks) Joint affected Minor flares after antibiotic treatment* ESR (mm/h) CRP (mg/dl) Serum Bb IgG % of cut off at baseline Serum Bb IgM positive test at baseline PCR positive test for Bb in joint fluid Intraarticular GC before antibiotic therapy
46 Male Yes No 3 Left knee None 32 13 2423 Yes Yes Yes
54 Male Yes No 1 Left knee None 55 89 700 No Yes Yes
47 Female Yes No 1 Right knee One 45 1 1350 Yes Yes No
68 Male Yes No 104 Left knee Two 13 51 1550 Yes Yes Yes
65 Male Yes No 1 Left knee Two 48 129 1200 +/- Yes Yes
70 Female Yes No 7 Right knee None 13 1 1500 No No No
50 Female Yes Yes 3 Left knee None 9 2 2273 Yes No No
49 Male Yes Yes 1 Left ankle None 37 74 2400 No No No
50 Male Yes Yes 1 Right knee None 23 33 2335 Yes NA Yes
59 Male Yes No 3 Left knee One 32 13 2423 Yes No No
54 Female No No 1.5 Left knee None 9 1 1350 No Yes Yes
55 Male No No 12 Right knee One 38 24 1350 No Yes Yes
66 Male No No 2.5 Right knee None 67 NA NA Yes No
51 Female Yes Yes 12 Right knee None 20 1 1450 No Yes No
50 Female No No 5 Left knee None 15 30 NA NA Yes No
47 Male No No 2 Left knee None 29 93 1300 +/- Yes No
Probable
Age (years) Gender History of prior tick bite History of prior EM Duration of arthritis (weeks) Joint affected Minor flares after antibiotic treatment* ESR (mm/h) CRP (mg/dl) Serum Bb IgG % of cut off at baseline Serum Bb IgM positive test at baseline

PCR positive test for Bb in

joint

fluid

Intraarticular GC before antibiotic therapy
41 Male Yes No 0 Left ankle None 8 53 2100 No No No
80 Male No No 3 Left knee 35 3 2550 No No No
53 Female Yes No 2 Both knees and several small joints in left foot (MTP and PIP-joints) One 68 90 2500 No No No
50 Male No No 0 Right knee None 68 132 1750 Yes No No
56 Female Yes Yes 4 Left knee 15 1 1300 Yes No No

EM: Erythema migrans. ESR: Erythrocyte sedimentation rate. CRP: C-reactive protein. Bb: Borrelia burgdorferi. IgG: Immunoglobulin type G. IgM: Immunoglobulin type M. PCR: Polymerase chain reaction. GC: Glucocorticosteroids. NA: Not assessed. MTP: Metatarsophalangeal joints. PIP: Proximal interphalangeal joints.

*Defined as episodes of arthritis symptoms the patients reported the first weeks/months after antibiotic treatment.

+/- Non conclusive test.

†Concomitant osteoarthritis with recurrent episodes of joint effusion.

Haugeberg et al.

Haugeberg et al. BMC Infectious Diseases 2014 14:185   doi:10.1186/1471-2334-14-185

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