Table 2

Log likelihood values and parameter estimated under two models of selection pressure within particular clades of NS5A quasispecies
Patient Model l 2Δl Estimates
P08 one-ratio −4404.76677 ωB = 0.1692
two-ratio −4404.28734 0.9587 ωB = 0.1521
ωF = 0.1872
P11a one-ratio −4558.41000 ωB = 0.1835
two-ratio −4552.47248 **11.8750 ωB = 0.1650
ωF = 0.5783
two-ratio −4553.77795 **9.264 ωB = 0.1419
ωF = 0.2685
P146 one-ratio −4755.95340 ωB = 0.1705
two-ratio −4755.92063 0.0822 ωB = 0.1727
ωF = 0.1618
two-ratio −4754.96926 1.9683 ωB = 0.1818
ωF = 0.1246
P44 one-ratio −6356.59235 ωB = 0.1433
two-ratio −6356.28458 0.6155 ωB = 0.1338
ωF = 0.1521
P03 one-ratio −3854.07081 ωB = 0.2003
two-ratio −3853.33452 1.4726 ωB = 0.1977
ωF = 0.2350
P42 one-ratio −5111.91233 ωB = 0.1101
two-ratio −5111.91231 0.0004 ωB = 0.1102
ωF = 0.1101
P47a one-ratio −5455.19420 ωB = 0.2013
two-ratio −5451.97704 *6.4343 ωB = 0.1604
ωF = 0.2487
two-ratio −5444.44505 **21.4983 ωB = 0.1776
ωF = 0.7177

Non-responder: P08, P11, P146, P44; End-of-treatment responder: P03, P42, P47.

X2 critical values, 1 df: *: 3.84; **: 6.63; 2Δ ℓ = 2 (l1-l0).

The ω values considered are presented in bold.

a Two clades selected for analyses.

Jardim et al.

Jardim et al. BMC Infectious Diseases 2013 13:61   doi:10.1186/1471-2334-13-61

Open Data