Table 2

Risk factors for ICU admission among 2751 HIV positive patients attending King’s College Hospital, South London, UK
Crude IRR P-value Adjusted IRR P-value
Age (per 10 year increase) 1.39 (1.17, 1.66) 0.001 1.21 (0.95, 1.54) 0.13
Female sex 1.46 (1.22, 2.20) 0.03 1.11 (0.79, 3.48) 0.48
Black ethnicity 0.99 (0.65, 1.52) 0.99
HIV risk factor
Heterosexual 1 1
Homosexual 0.57 (0.33, 0.98) 0.04 0.64 (0.33, 1.25) 0.19
IVDU 1.79 (0.81, 3.95) 0.15 1.01 (0.34, 2.96) 0.99
Hepatitis B surface antigen positive 1.95 (0.99, 3.82) 0.07 1.46 (0.65, 3.28) 0.36
Hepatitis C antibody positive 0.63 (0.23, 1.73) 0.94
AIDS (CDC-C) 9.58 (5.42, 16.9) <0.0001 6.94 (3.73, 12.9) <0.0001
CD4 cell count (cells/mm3)
>350 1 1
200-350 1.01 (0.48, 2.02) 1.00 0.98 (0.45, 2.15) 0.97
100-200 2.89 (1.39, 5.85) 0.003 2.22 (1.01, 4.88) 0.05
50-100 12.5 (6.35, 24.6) <0.0001 2.70 (0.92, 7.98) 0.07
<50 21.0 (11.7, 37.8) <0.0001 6.11 (2.99, 12.5) <0.0001
Initiated cART 0.17 (0.11, 0.27) <0.0001 0.11 (0.07, 0.19) <0.0001
HIV RNA <400 copies/mL 0.73 (0.44, 1.24) 0.31

CD4 cell count, cART status and HIV RNA level are included as time-updated variables.

cART-combination antiretroviral therapy.

Shrosbree et al.

Shrosbree et al. BMC Infectious Diseases 2013 13:23   doi:10.1186/1471-2334-13-23

Open Data