Table 7

Sensitivity analysis results
Results Year Five-year results
1 2 3 4 5
Unfavourable scenario
 Avoided hospitalized pneumonias 785 3,749 8,690 14,925 21,993 50,141
 Avoided outpatient pneumonias 528 2,520 5,841 10,033 14,784 33,707
 Avoided primary bacteremias 21 102 208 398 503 1,232
 Avoided empyemas 0 1 3 5 7 17
 Avoided meningitis 7 34 69 131 166 406
 Avoided bacteremic pneumonias 49 237 484 924 1,169 2,863
Avoided contagions 1,390 6,643 15,294 26,417 38,621 88,366
 Hospitalized pneumonia cost savings 1,400,564 6,691,314 15,508,174 26,637,024 39,250,376 89,487,451
 Outpatient pneumonia cost savings 118,698 567,092 1,314,325 2,257,501 3,326,488 7,584,104
 Primary bacteremias cost savings 78,398 374,823 766,424 1,464,809 1,852,303 4,536,757
 Empyemas cost savings 1,549 7,405 15,141 28,937 36,592 89,623
 Meningitis cost savings 70,727 338,147 691,432 1,321,482 1,671,060 4,092,848
 Bacteremic pneumonias cost savings 241,340 1,153,848 2,359,348 4,509,247 5,702,099 13,965,882
Savings by all cases averted 1,911,277 9,132,628 20,654,844 36,218,999 51,838,917 119,756,665
 Cost of vaccinations 13,878,696 13,878,696 13,878,696 13,878,696 13,878,696 69,393,481
 Net healthcare cost 11,967,420 4,746,068 −6,776,147 −22,340,303 −37,960,221 −50,363,184
Discounted net healthcare cost 11,967,420 4,520,065 −6,146,165 −19,298,394 −31,229,968 −40,187,043
Favourable scenario
 Avoided hospitalized pneumonias 1,744 8,632 18,959 29,239 38,179 96,754
 Avoided outpatient pneumonias 1,172 5,803 12,745 19,656 25,666 65,042
 Avoided primary bacteremias 47 234 454 779 873 2,387
 Avoided empyemas 1 3 6 11 12 32
 Avoided meningitis 16 77 150 257 288 787
 Avoided bacteremic pneumonias 110 545 1,055 1,811 2,029 5,550
Avoided contagions 3,090 15,294 33,369 51,753 67,047 170,552
 Hospitalized pneumonia cost savings 3,804,001 18,829,047 41,355,130 63,780,008 83,280,575 211,048,761
 Outpatient pneumonia cost savings 322,391 1,595,771 3,504,867 5,405,386 7,058,069 17,886,484
 Primary bacteremias cost savings 212,934 1,054,733 2,043,798 3,507,357 3,930,174 10,748,996
 Empyemas cost savings 4,206 20,836 40,375 69,287 77,640 212,345
 Meningitis cost savings 192,099 951,530 1,843,818 3,164,172 3,545,617 9,697,236
 Bacteremic pneumonias cost savings 655,491 3,246,874 6,291,595 10,769,994 12,098,587 33,089,542
Savings by all cases averted 5,191,122 25,698,792 55,079,583 86,723,204 109,990,663 282,683,364
 Cost of vaccinations 18,504,928 18,504,928 18,504,928 18,504,928 18,504,928 92,524,641
 Net healthcare cost 13,313,807 −7,193,863 −36,574,655 −68,218,276 −91,485,735 −190,158,723
Discounted net healthcare cost 13,313,807 −7,193,863 −36,574,655 −68,218,276 −91,485,735 −190,158,723

Pradas et al.

Pradas et al. BMC Infectious Diseases 2013 13:175   doi:10.1186/1471-2334-13-175

Open Data