Table 1

Preliminary evaluation: performance of three syphilis serological assays using Dried Blood Spots compared to plasma
Plasma as reference (using the same assay) Positive samples detected Negative samples detected Sensitivity (95% CI)* Specificity (95% CI)*
DBS TPPA(n=463) 82/96 363/367 85.4% 98.9%
(76.7–91.8%) (97.2–99.7%)
DBS EIA (n=282) 53/56 114/226 94.6% 50.4%
(85.1–98.9%) (43.7–57.1%)
DBS TPHA(n=445) 46/91 353/354 50.5% 99.7%
(39.9–61.2%) (98.4–100%)

n= samples.

* 95% confidence interval.

1 TPPA DBS indeterminate excluded.

19 TPHA indeterminate results excluded.

Smit et al.

Smit et al. BMC Infectious Diseases 2013 13:102   doi:10.1186/1471-2334-13-102

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