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This article is part of the supplement: Proceedings of the Second Workshop of the Regional Study Group on HCV in the Calabria Region (Southern Italy). The virus-host-therapy pathway in HCV disease management: from bench to bedside in the era of Directly Acting Antivirals

Open Access Review

Epidemiological features and specificities of HCV infection: a hospital-based cohort study in a university medical center of Calabria region

MC Liberto*, N Marascio, E Zicca and G Matera

Author Affiliations

Department of Health Sciences, Institute of Microbiology, University “Magna Graecia” of Catanzaro, 88100, Catanzaro, Italy

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BMC Infectious Diseases 2012, 12(Suppl 2):S4  doi:10.1186/1471-2334-12-S2-S4

Published: 12 November 2012

Abstract

The epidemiological status of HCV in Europe, and in particular in Mediterranean countries, is continuously evolving. The genotype distribution is related to improvement of healthcare conditions, expansion of intravenous drug use and immigration. We review and characterize the epidemiology of the distribution of HCV genotypes within Calabria, an area of Southern Italy. We focus on the pattern of distinct HCV genotype changes over the last 16 years; particularly subtype 1b and genotype 4. We collected data by evaluating a hospital-based cohort of chronic hepatitis C patients; in addition, we report an update including new patients enrolled during last eight months.