This article is part of the supplement: Abstracts from the First International Science Symposium on HIV and Infectious Diseases (HIV SCIENCE 2012)
Development of a vaccine delivery system using hepatitis B core antigen based VLPs to deliver mycobacterial antigens
Mycobacterium Research Group, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, India
BMC Infectious Diseases 2012, 12(Suppl 1):P9 doi:10.1186/1471-2334-12-S1-P9Published: 4 May 2012
First paragraph (this article has no abstract)
Growing prevalence of TB and the emergence of XDR-TB have stimulated substantial efforts to develop better vaccines for TB. Recent researches have shown that some of the antigenic proteins and fusion of different proteins produced by Mycobacterium tuberculosis can give protection in animal models when administrated with specific adjuvants. In the present study, we explored the use HBcag-VLPs for delivery of tuberculosis antigens.