Table 2

Type of CMV testing and timing of CMV testing among pregnant womena and among pregnant womena with a diagnostic code for CMV, MarketScan 2009
Pregnant womena with CMV-specific testingb Pregnant womena with an ICD-9-CM diagnostic code for CMV disease and CMV-specific testingb
N, 1,668 N, 10
# % # %
Type of CMV-specific Testb
CMV PCR ONLY 17 1% 1 10%
CMV DFA ONLY 1 0% 0 0%
CMV Serology ONLY (CMV IgG, IgM, and EIA) 741 44% 5 50%
CMV PCR AND CMV Serology 8 0% 0 0%
CMV PCR AND Non-Specific Culture or PCR 24 1% 2 20%
CMV PCR, CMV Serology, AND Non-specific Culture or PCR 13 1% 0 0%
CMV DFA, CMV Serology, AND Non-Specific Culture or PCR 1 0% 0 0%
CMV Serology AND Non-specific Culture or PCR 863 52% 2 20%
Gestational Age when CMV-Specific Testing Conductedc
1st Trimester 863 52% 5 50%
2nd Trimester 395 24% 4 40%
3rd Trimester 410 24% 1 10%

Note: CMV, cytomegalovirus; ICD-9-CM, International Classification of Diseases-9th revision, Clinical Modification; PCR, polymerase chain reaction; IgG, Immunoglobulin G; IgM, Immunoglobulin M; DFA, direct fluorescent testing; EIA, enzyme immunoassay.

aPregnant women defined as female enrollees who were 1) aged 15–44 years, 2) enrolled for the entire year in 2009, and 3) had a delivery code (defined in Appendix) between October-December 2009.

bCMV-specific testing includes CMV IgG, CMV IgM, CMV DFA, CMV EIA, and CMV PCR testing.

cDate of first claim with a delivery code (defined in Appendix) was used to approximate delivery date in order to calculate the approximate age when the first CMV-specific testing was done. We assumed that CMV-specific testing which occurred 0–13 weeks was within the 1st trimester, testing within weeks 14–26 to be in the 2nd trimester, and testing within weeks 27–42 to be in the 3rd trimester. Pregnant women with testing that occurred before (<0 weeks) or after (≥43 weeks) pregnancy were excluded.

Leung et al.

Leung et al. BMC Infectious Diseases 2012 12:334   doi:10.1186/1471-2334-12-334

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