Table 2

Demographics and clinical characteristics of hemodialysis patients with and without methicillin-resistant S. aureus (MRSA) colonization
Demographic and clinical data No. (%) of subjects Odds ratio 95% Confidence interval p valuea
Total (n=296) MRSA (n=19) Non-MRSA (n=277)
Male 136(45.9) 6(31.6) 130(46.9) 0.522 0.193~1.413 0.194
Age
19-29 6(2.0) 0 6(2.1) 0.934 0.906~0.963 1.000
30-59 155(52.4) 10(52.6) 145(52.3) 1.011 0.399~2.566 0.981
≥60 135(45.6) 9(47.4) 126(45.5) 1.079 0.425~2.737 0.873
Underlying diseases
DM 125(42.2) 11(57.9) 114(41.2) 1.966 0.767~5.041 0.153
Hypertension 194(65.5) 16(84.2) 178(64.3) 2.920 0.830~10.268 0.081
HBV carrier 32(10.8) 0 32(11.6) 0.928 0.897~0.960 0.241
HCV carrier 46(15.5) 2(10.5) 44(15.9) 0.620 0.138~2.781 0.406
Liver cirrhosis 8(2.7) 0 8(2.3) 0.934 0.905~0.963 1.000
Gastric ulcer 92(31.1) 5(26.3) 87(31.4) 0.780 0.272~2.234 0.643
History of GI bleeding 26(8.8) 3(15.8) 23(8.3) 2.071 0.562~7.635 0.226
Asthma 2(0.7) 0 2(0.7) 0.935 0.908~0.964 1.000
History of TB infection 5(1.7) 0 5(1.8) 0.935 0.907~0.964 1.000
COPD 16(5.4) 0 16(5.8) 0.932 0.903~0.962 0.610
Cancer 25(8.4) 1(5.3) 24(8.7) 0.586 0.075~4.580 1.000
Current disease
Pneumonia 3(1.0) 0 3(1.1) 0.935 0.907~0.964 1.000
URTI 51(17.2) 4(21.1) 47(17.0) 1.305 0.415~4.108 0.752
Other risk factors
Hospitalization c 95(32.1) 4(21.1) 91(35.0) 0.545 0.176~1.689 0.287
Previous S. aureus infection c,d 42(14.2) 4(21.1) 38(13.7) 1.677 0.529~5.323 0.325
S. aureus skin infection c,d,e 13(4.4) 1(5.3) 12(4.3) 1.227 0.151~9.970 0.586
Previous catheter related infectionc 34(11.5) 3(15.8) 31(11.2) 1.488 0.410~5.397 0.467
Using of immunosuppressant 18(6.1) 2(10.5) 16(5.8) 1.919 0.407~9.039 0.324
Alcohol drinking 24(8.1) 0 24(8.7) 0.930 0.900~0.961 0.381
Average duration of HD(year)b 7.03±0.35 5.60±1.28 7.13±0.36 0.289
Duration > 3 years 11(57.9) 195(70.4) 206(69.6) 0.578 0.224~1.490 0.252
Duration > 5 years 8(42.1) 152(54.9) 160(54.1) 0.598 0.233~1.533 0.280
Blood access
Hickman 22(7.4) 1(5.3) 21(7.6) 0.677 0.086~5.326 1.000
A-V fistula 180(60.8) 11(57.9) 169(61.0) 0.879 0.342~2.254 0.788
Gortex 94(31.8) 7(36.8) 87(31.4) 1.274 0.485~3.347 0.623
Other catheterf 8(2.7) 2(10.5) 6(2.2) 5.314 0.997~28.331 0.087

DM: diabetes mellitus, HBV: hepatitis B virus , HCV: hepatitis C virus, GI: gastrointestinal, TB: tuberculosis, COPD: chronic obstructive pulmonary disease, URTI: upper respiratory tract infection, inf.: infection, HD: hemodialysis, A-V: arterial venous.

a For categorical variables, Fisher’s exact test was used for extreme proportions (expected count <5) instead of Pearson’s chi-square test.

b data was presented as the mean value ± standard error of the mean for continuous variables. Performed by Student t test.

c any event happened in one year before sampling.

d including general S. aureus infection without known susceptibility or resistance of antibiotics.

e including impetigo, furuncle, carbuncle, cellulitis, and abscess.

f including Foley and tracheostomy tube.

Kang et al.

Kang et al. BMC Infectious Diseases 2012 12:284   doi:10.1186/1471-2334-12-284

Open Data