Table 4

Patient’s clinical characteristics on the day of infection (D0) and PCT kinetics the next 6 days after diagnosis of CRBSI
Controlled Not controlled P
n = 16 n = 10
WBC count [103/μl; mean (SD)] 15.69 (6.9) 14.87 (4.5) 0.745a
CRP [mg/dl; median (IQR)] 15.78 (10.06-21.05) 15.65 (10.55-25.75) 0.732c
SOFA score [mean (SD)] 6.56 (2.19) 8.20 (3.22) 0.135a
Shock [no (%)] 7 (43.8) 7 (70.0) 0.191b
PCT [ng/mL; median (IQR)]
D0 (16/10) d 7.55 (2.50-13.67) 8.30 (2.07-11.35) 0.771c
D + 1 (16/10) d 2.50 (1.53-10.52) 3.00 (1.30-5.55) 0.635c
D + 2 (16/10) d 1.75 (0.65-5.22) 2.70 (1.22-4.27) 0.635c
D + 3 (16/10) d 0.55 (0.50-3.10) 2.60 (0.75-5.12) 0.047c
D + 4 (16/10) d 0.50 (0.23-2.15) 2.40 (0.67-6.00) 0.042c
D + 5 (16/10) d 0.20 (0.13-0.72) 2.40 (0.35-8.17) 0.009c
D + 6 (16/9) d 0.20 (0.12-0.50) 2.10 (0.20-12.25) 0.012c
ΔPCTD0, D+1 −2.65 (−8.90 to −0.75) −4.60 (−5.63 to −0.78) 0.895c
ΔPCTD+1, D+2 −1.65 (−5.45 to −0.38) −0.30 (−1.30 to −0.08) 0.037c
ΔPCTD+2, D+3 −1.00 (−2.68 to −0.15) −0.05 (−0.45 to 0.25) 0.017c
ΔPCTD+3, D+4 −0.15 (−1.65 to −0.03) −0.15 (−0.28 to 0.73) 0.253c
ΔPCTD+4, D+5 −0.25 (−0.68 to −0.12) −0.10 (−0.33 to 0.75) 0.085c
ΔPCTD+5, D+6 0.00 (−0.10 to 0.08) 0.00 (−0.45 to 0.20) 0.872c

a Student’s t test; b Chi-square test; c Mann–Whitney test; d No of patients available for analysis (Controlled/Not controlled).

Theodorou et al.

Theodorou et al. BMC Infectious Diseases 2012 12:247   doi:10.1186/1471-2334-12-247

Open Data