Table 2

Diagnostic performance of conventional nested Aspergillus PCRa
Sensitivity Specificity PPV NPV
As compared to EORTC/NIAID
Proven 0% 71% 0% 98%
Proven & Probable 36% 72% 7% 95%
Proven & Probable & Possible 26% 70% 26% 71%
As compared to clinical judgment
Receiving antifungal therapy 30% 73% 60% 43%
Suspicion of IFD on radiologic studies 28% 71% 27% 72%

IFD = invasive fungal disease.

Buess et al.

Buess et al. BMC Infectious Diseases 2012 12:237   doi:10.1186/1471-2334-12-237

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