Table 4

Surgical procedures performed and patient outcomes by infection type
Overall Diabetic foot infection Surgical site infection Deep soft tissue abscess Cellulitis
(N=1,033) (N=278) (N=330) (N=147) (N=278)
Surgical procedures related to study infection: N (%) 426 (41.2) 123 (44.2) 148 (44.8) 100 (68.0) 55 (19.8)
For source control: N (%) 181 (17.5) 56 (20.1) 48 (14.5) 56 (38.1) 21 (7.6)
 Incision and drainage 117 (11.3) 25 (8.9) 29 (8.8) 47 (32.0) 16 (5.8)
 Surgical debridement 41 (3.9) 11 (3.9) 18 (5.5) 8 (5.4) 4 (1.4)
 Excision of wound 5 (0.4) 3 (1.1) 0 (0.0) 1 (0.7) 1 (0.4)
 Amputation 18 (1.7) 17 (6.1) 1 (0.3) 0 (0.0) 0 (0.0)
Clinical assessment: N (%)
 Resolved/cured 82 (7.9) 22 (7.9) 15 (4.6) 12 (8.2) 33 (11.9)
 Improved 836 (80.9) 213 (76.6) 274 (83.0) 131 (89.1) 218 (78.4)
 Unchanged 32 (3.1) 10 (3.6) 13 (3.9) 0 (0.0) 9 (3.2)
 Worsened 6 (0.6) 3 (1.1) 2 (0.6) 0 (0.0) 1 (0.4)
 Missing 77 (7.5) 30 (10.8) 26 (7.9) 4 (2.7) 17 (6.1)
Quality of life^
 Change in EQ-5D Index at discharge: mean (median, range) 0.1 (0.1, -0.8-0.9) 0.1 (0.1, -0.8-0.9) 0.1 (0.1, -0.7-0.9) 0.2 (0.2, -0.3-0.7) 0.2 (0.1, -0.7-0.8)
 Change in EQ-VAS at discharge: mean (median, range) 11.7 (10, -93-100) 11.4 (10, -93-92) 11.5 (10, -55-90) 13.7 (10, -45-100) 11.1 (10, -50-85)
 Length of stay: mean (median, range) 7.1 (5, 1–55) 7.6 (6, 1–26) 8.1 (6, 1–55) 5.8 (5, 2–31) 6.0 (5, 1–35)
Hospital mortality: N (%) 4 (0.4) 2 (0.7) 2 (0.6) 0 (0.0) 0 (0.0)

^Note: Quality of life scores were calculated only for a portion of the total patient population with available data (99.4% for EQ-5D Index at baseline, 89.7% for change in EQ-5D Index at discharge, 99.3% for EQ-5D VAS at baseline, and 89.5% for change in EQ-5D VAS at discharge).

Lipsky et al.

Lipsky et al. BMC Infectious Diseases 2012 12:227   doi:10.1186/1471-2334-12-227

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