Renal function and tubular damage markers, at baseline and after 1 and 2 years, in the entire cohort, and in each treatment group. Patients were grouped according to the exposure to antiretrovirals: Group A = TDF, Group B = no TDF; Group C = TDF+PI, Group D = no TDF+PI. Statistical analysis related to baseline, 1 and 2 years in each group were performed through Friedman test. P-values related to analysis between group A versus group B and group C versus group D at each time point were obtained through Mann Whitney test (*), while those related to analysis between two time points among the same group with Wilcoxon matched-paired signed rank test (#).
Pontrelli et al. BMC Infectious Diseases 2012 12:18 doi:10.1186/1471-2334-12-18