Receiver operating characteristics (ROC) curves of delta neutrophil index (DNI) and other laboratory markers for differentiating between the presence and absence of severe sepsis/septic shock. Areas under ROC were 0.92 (95% CI, 0.86-0.98) for DNI, 0.53 (95% CI, 0.41-0.64) for white blood cell (WBC), 0.76 (95% CI, 0.61-0.82) for lactate, and 0.64 (95% CI, 0.53-0.75) for C-reactive protein (CRP). The accuracy of DNI for discriminating between the presence and absence of severe sepsis/septic shock was superior to those of other laboratory markers (p < 0.05).
Park et al. BMC Infectious Diseases 2011 11:299 doi:10.1186/1471-2334-11-299