Table 2

Propensity score adjusted associations between receipt of nafcillin or cefazolin versus vancomycin and 30-day in-hospital mortality

Association

Adjusted hazard ratio and 95% confidence interval

Variables included in the propensity score


Receipt of nafcillin or cefazolin versus vancomycin and 30-day in-hospital mortality

0.21 (0.09, 0.47)

Severity of illness

Aggregate comorbidity

Admission to the ICU

Age

Hemodialysis

Endocarditis

Time to receipt of appropriate therapy

Receipt of other anti

-staphylococcal antibiotic


Switch from vancomycin to nafcillin or cefazolin versus remaining on vancomycin and 30-day in-hospital mortality

0.31 (0.10, 0.95)

Severity of illness

Aggregate comorbidity

Admission to the ICU

Community-associated infection

Hemodialysis

Age

Endocarditis

Time to receipt of appropriate therapy


Schweizer et al. BMC Infectious Diseases 2011 11:279   doi:10.1186/1471-2334-11-279

Open Data