Open Access Highly Accessed Research article

A comparative epidemiologic analysis of SARS in Hong Kong, Beijing and Taiwan

Eric HY Lau1, C Agnes Hsiung2, Benjamin J Cowling1*, Chang-Hsun Chen3, Lai-Ming Ho1, Thomas Tsang4, Chiu-Wen Chang3, Christl A Donnelly5 and Gabriel M Leung1

Author Affiliations

1 School of Public Health, The University of Hong Kong, Pokfulam Road, Hong Kong

2 Division of Biostatistics and Bioinformatics, Institute of Population Health Sciences, National Health Research Institutes, 35, Keyan Road, Zhunan, Miaoli County 35053, Taiwan

3 Second Division of Centers for Disease Control, No 6, Linshen South Road., Taipei, Taiwan

4 Centre for Health Protection, Department of Health, Government of the Hong Kong Special Administrative Region, 147C Argyle Street, Kowloon, Hong Kong

5 MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College, St Mary's Campus, Norfolk Place, London W2 1PG, UK

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BMC Infectious Diseases 2010, 10:50  doi:10.1186/1471-2334-10-50

Published: 6 March 2010

Additional files

Additional file 1:

Characteristics of SARS patients in Hong Kong, Beijing and Taiwan. The associated case-fatality ratios and adjusted odds ratios (95% confidence intervals) are also reported. CFR, case fatality ratio; AOR, adjusted odds ratio; CI, confidence interval. * Patients with unknown age, pre-existing comorbid conditions or admission date were excluded. Adjusted for sex, age, health care worker status, preexisting comorbid conditions and nosocomial infection. Data on final outcome were not available for 12 patients in Taiwan and were excluded for analysis. § The estimates were not shown as there was not more than 2 deaths in these age groups out of a relatively large number of patients. || Based on the WHO World Standard Population distribution [16].

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Additional file 2:

Characteristics of SARS patients in Hong Kong, Beijing and Taiwan (pooled data). The associated case-fatality ratios and adjusted odds ratios (95% confidence intervals) are also reported. CFR, case fatality ratio; AOR, adjusted odds ratio; CI, confidence interval. * Data on final outcome were not available for 12 patients in Taiwan and were excluded for analysis. Patients with unknown age, pre-existing comorbid conditions or admission date were excluded from multivariable logistic regression models. Adjusted for sex, age, health care worker status, preexisting comorbid conditions, nosocomial infection and region. Based on the WHO World Standard Population distribution [16].

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Additional file 3:

Case fatality ratio by different onset-to-admission periods, Hong Kong, Beijing and Taiwan. CFR, case fatality ratio; CI, confidence interval. * Excluding 16 patients with unknown admission dates or discharge outcome.

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Additional file 4:

Case fatality ratio by different onset-to-admission periods in Beijing, XTS Hospital, Hospital 302 and Hospital 309. CFR, case fatality ratio; CI, confidence interval.

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Additional file 5:

Factors affecting the onset-to-death and onset-to-discharge period of SARS patients in Hong Kong, Beijing and Taiwan. CI, confidence interval. * The acceleration factor is computed as exp(β). It indicates the relative increase (>1) or decrease (<1) in the median time from onset of symptoms to death or discharge. also adjusted for interaction between location with admission before symptom onset. also adjusted for interaction between location with health care worker and pre-existing comorbid conditions.

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Additional file 6:

Factors affecting the onset-to-death and onset-to-discharge period of SARS patients in Hong Kong, Beijing (restricted to Hospitals 302 and 309 only and Taiwan. CI, confidence interval. * The acceleration factor is computed as exp(β). It indicates the relative increase (>1) or decrease (<1) in the median time from onset of symptoms to death or discharge. also adjusted for interaction between location with admission before symptom onset. also adjusted for interaction between location with health care worker and pre-existing comorbid conditions.

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