Table 3

Relative rates* of type-specific and combined HPV infection clearance according to viral load

Relative rate (95%CI)


HPV type

Viral load tertile

No. of Events/No. Eligible cases

Unadjusted

Adjusted


16

Third

5/27

1.0

1.0

Second

8/27

1.52 (0.49-4.69)

1.31 (0.41-4.20)

First

13/27

2.55 (0.90-7.24)

2.38 (0.82-6.89)


18

Third

4/13

1.0

1.0

Second

3/13

1.64 (0.31-8.78)

1.14 (0.18-7.35)

First

11/13

4.76 (1.23-18.45)

4.61 (1.17-18.05)


31

Third

6/10

1.0

1.0

Second

3/10

0.87 (0.21-3.69)

0.80 (0.19-3.44)

First

2/9

0.67 (0.16-2.75)

0.66 (0.15-2.97)


45

Third

3/6

1.0

1.0

Second

4/6

1.99 (0.21-19.02)

1.59 (0.15-16.91)

First

3/6

2.25 (0.20-25.09)

2.06 (0.17-24.27)


Above HPV types combined

Third

20/55

1.0

1.0

Second

22/55

1.45 (0.79-2.64)

1.49 (0.81-2.74)

First

24/56

2.11 (1.16-3.86)

2.21 (1.19-4.10)


* Using Cox proportional hazards regression. Rate of clearance for third viral load tertile (highest) taken as referent. For the analysis of combined types the observations are not independent and required a robust variance estimator. Adjusted relative rates were estimated in models that included age and sexual partners as covariates.

Ramanakumar et al. BMC Infectious Diseases 2010 10:326   doi:10.1186/1471-2334-10-326

Open Data