Table 1

Hospitalized adult patients with 2009 Influenza A (H1N1) in Beijing: demographics, comorbidities, and clinical presentation

Survivor

(n = 128)

Nonsurvivor

(n = 27)

Total

(n = 155)

P value


Male sex

73 (57.0%)

17 (63.0%)

90 (58.1%)

0.570

Age, year

42.4 ± 18.2

45.9 ± 20.7

43.0 ± 18.6

0.388

Ethnicity

Han Chinese

127 (99.2%)

25 (92.6%)

152 (98.1%)

0.079

Smoker

28 (21.9%)

7 (25.9%)

35 (22.6%)

0.647

No comorbidity

60 (46.9%)

14 (51.9%)

74 (47.7%)

0.609

Comorbidity

Cardiovascular disease

34 (26.6%)

11 (40.7%)

45 (29.0%)

0.140

Hypertension

25 (19.5%)

10 (37.0%)

35 (22.6%)

0.048

Ischemic heart disease

19 (14.9%)

5 (18.5%)

24 (15.5%)

0.572

Chronic lung disease

19 (14.9%)

3 (11.1%)

22 (14.2%)

0.768

COPD

8 (6.3%)

2 (7.4%)

10 (6.5%)

0.686

Diabetes

13 (10.2%)

7 (25.9%)

20 (12.9%)

0.051

Pregnancy or postpartum

12 (9.4%)

2 (7.4%)

14 (9.0%)

1.000

Pregnancy

11 (8.6%)

1 (3.7%)

12 (7.7%)

0.693

Postpartum < 1 month

1 (0.8%)

1 (3.7%)

2 (1.3%)

0.319

Cerebral vascular disease

6 (4.7%)

3 (11.1%)

9 (5.8%)

0.191

Symptoms at disease onset

Fever (> 37.8°C)

121 (94.5%)

24 (88.9%)

145 (93.5%)

0.380

Cough

117 (91.4%)

25 (92.6%)

142 (91.6%)

1.000

Dyspnea

56 (43.8%)

17 (63.0%)

73 (47.1%)

0.069

Sore throat

42 (32.8%)

4 (14.8%)

46 (29.7%)

0.063

Myalgia

24 (18.8%)

3 (11.1%)

27 (17.4%)

0.416

Rhinorrhea

21 (16.4%)

3 (11.1%)

24 (15.5%)

0.770

Hemoptysis

15 (11.7%)

4 (14.8%)

19 (12.3%)

0.746

Diarrhea

6 (4.7%)

1 (3.7%)

7 (4.5%)

1.000

Vomiting

5 (3.9%)

0

5 (3.2%)

0.588

Time from symptoms to hospital admission, day*

5.0 (3.0, 7.0)

6.0 (3.5, 7.0)

5.0 (3.0, 7.0)

0.376

Clinical presentation on admission

Dyspnea

61 (47.7%)

21 (77.8%)

82 (52.9%)

0.004

Pneumonia on CXR

104 (81.3%)

25 (92.6%)

129 (83.2%)

0.254

Laboratory tests on admission

White cell count, 109/L

6.1 ± 3.7

7.3 ± 5.1

6.3 ± 4.0

0.183

Lymphocyte, 109/L

1.2 ± 1.4

0.7 ± 0.3

1.1 ± 1.3

0.118

CPK, U/L

339 ± 620

538 ± 548

373 ± 610

0.222

CK-MB, μg/L

23 ± 33

29 ± 22

24 ± 31

0.457

cTnI, μg/L

0.16 ± 0.23

0.32 ± 0.69

0.21 ± 0.43

0.417

LDH, U/L

356 ± 240

744 ± 759

432 ± 422

0.041

Total bilirubin, μmol/L

20.2 ± 57.8

48.8 ± 156.6

25.8 ± 86.2

0.431

AST, U/L

57 ± 49

348 ± 803

113 ± 366

0.105

ALT, U/L

51 ± 111

123 ± 254

65 ± 152

0.209


ALT, alanine transaminase; AST, aspartate transaminase; CK-MB, creatine kinase-MB; COPD, chronic obstructive pulmonary disease; CPK, creatine phosphokinase; cTnI, cardiac troponin I; CXR, chest-X ray; LDH, lactate dehydrogenase

*expressed as median (interquartile range)

Xi et al. BMC Infectious Diseases 2010 10:256   doi:10.1186/1471-2334-10-256

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