Table 1 |
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Model parameters, together with baseline value and range if varied during analysis. |
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Parameter |
Description |
Value (Range) |
Refs |
|
|
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|
gE |
Rate of transition from latent to prodromal |
1/12 days-1 |
[14] |
|
|
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|
gP |
Rate of transition from prodromal to infectious |
1/2.5 days-1 |
[15] |
|
|
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|
gI |
Rate of transition from infectious to removed |
1/8.6 days-1 |
[16] |
|
|
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|
δ |
Case fatality risk |
30% |
|
|
|
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|
θ |
Probability of case isolation success |
90% |
[21] |
|
|
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|
gQ |
Rate of transition from isolated to removed |
1/20 days-1 |
[5] |
|
|
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|
ϵ |
Probability of contact tracing success |
80% |
[5] |
|
|
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|
ϵ1 |
Vaccine efficacy when susceptible |
97.5% |
[14] |
|
|
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|
ϵ2 |
Vaccine efficacy when latent |
30% |
[23] |
|
|
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|
gO |
Rate of transition from observed to removed or vaccinated |
1/15 days-1 |
[5] |
|
|
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|
γ |
Proportion of population contraindicated for mass vaccination |
30% |
[25] |
|
|
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|
E0 |
Number of index cases |
10 |
see text |
|
|
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|
|
Number of index cases for secondary outbreak |
1 |
see text |
|
|
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|
Itrig |
Number of clinical cases prior to detection |
4 |
see text |
|
|
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|
|
Number of clinical cases prior to detection for secondary outbreak |
1 |
see text |
|
|
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|
δV |
Vaccine fatality risk |
10-5(0 -- 10-5) |
[24] |
|
|
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|
R0 |
Basic reproductive ratio |
5 (3 -- 7) |
[14] |
|
|
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|
RP |
Prodromal type reproductive ratio |
0.5 (0.1 -- 1.5) |
|
|
|
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|
κ |
Movement reductions when infectious |
0.9 (0 -- 1) |
[5] |
|
|
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|
v |
Rate of mass vaccination |
N/7 (see Figure 3(c)) |
see text |
|
|
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|
N |
Population size of region |
105(see Figure 3(a)) |
|
|
|
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|
ξ |
Region outwardness |
0.4 (see Figure 3(d)) |
|
|
|
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|
M |
Number of regions of same type as outbreak region |
n/a (see Figure 3(a)) |
|
|
|
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|
M0 |
Number of regions at relevant scale initially infected |
1 (1 -- 10) |
see text |
|
|
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|
n |
Neighbourhood size (contacts per individual) |
17 (5 -- 50) |
|
|
|
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|
ϕ |
Clustering coefficient |
0 (0 -- 0.5) |
see text |
|
|
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|
Either references are given, or the parameter value is discussed in the main text. Values referenced to [5] are typically also based on expert opinion from discussions with the Department of Health. [34] provides an example of the considerations involved in estimating these values |
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House et al. BMC Infectious Diseases 2010 10:25 doi:10.1186/1471-2334-10-25 |
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