Case report
Successful treatment of late Salmonella infections in total hip replacement - report of two cases
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* Corresponding authors: Kálmán Tóth tothk@szote.u-szeged.hu - Krisztián Sisák sisakkrisztian@hotmail.com
1 Department of Orthopaedics, University of Szeged, 6 Semmelweis Street, Szeged, 6720, Hungary
2 Department of Orthopaedics, County Hospital of Kecskemét, 39 Nyíri Road, Kecskemét, 6000, Hungary
3 Department of Orthopaedics, County Hospital of Szolnok, 21 Tószegi Street, Szolnok, 5004, Hungary
BMC Infectious Diseases 2010, 10:160 doi:10.1186/1471-2334-10-160
Published: 8 June 2010Abstract
Background
Salmonella species can be rarely isolated from periprosthetic joint infections, however when present, are usually part of a severe septic clinical picture.
Case presentations
Two patients presented with late infected hip replacements to our institution. The first patient with multiple comorbidities had a confirmed Salmonella Enteridis infection with an abscess in the groin, with loosening of both components. He underwent a successful one stage cemented revision hip replacement, followed by 6 weeks of antibiotic therapy (ciprofloxacin). He had no recurrence or complications. The second patient was admitted in a septic condition with ARDS to the Intensive Care Unit 7 years following an uncemented total hip replacement. From an ultrasound guided hip aspirate Salmonella cholerae-suis was isolated. He underwent a successful a two-stage revision hip replacement.
Conclusions
Successful treatment of such potentially life threatening infections is achievable using modern orthopaedic techniques and close collaboration with the infectious diseases specialists.