Table 3

Comparison of the clinical features and laboratory test abnormalities between patients with pneumonia and 2009 H1N1 influenza who died and those who survived in the First Affiliated Hospital of China Medical University during November 4 to December 31, 2009.

Clinical characteristic or laboratory test abnormalities

Died

Survived

P


data

n

data

n


Medical condition (no)

6

10

17

58

0.076

Cigarette index ≥ 400(no)

2

10

7

58

0.611

BMI ≥ 24(no)

9

10

33

58

0.045#

BMI 24-27.9

1

10

19

58

0.260

BMI ≥ 28

8

10

14

58

0.001#

Median age

43.5(24-63)

10

41(18-66)

58

0.562

Interval from onset of illness to initiation of antiviral therapy, in days

6(4-10)

10

7(2-15)

58

0.345

Lymphocyte count (×109/L)

0.58(0.02-1.15)

10

0.79(0.31-4.34)

58

0.025**

LDH(U/L)

2583(324-4340)

10

775(180-4104)

57

0.003**

CK(U/L)

299.5(25-2000)

10

165(20-4188)

57

0.268

AST(U/L)

84(16-225)

10

43(12-339)

58

0.091

ALT(U/L)

54(23-167)

10

41.5(11-204)

58

0.446

Alb(g/L)

27.3(18-33)

10

35(9.6-51)

58

0.003**

CRP (mg/mL)

9.515(2.32-27.1)

8

1.49(0.1-29.7)

57

0.001**

CD4 T cell count (/μL)

118.5(29-391)

8

470.5(86-1892)

56

<0.0005**

CD8 T cell count (/μL)

87(23-293)

8

307(44-1113)

56

<0.0005**

CD3 T cell count (/μL)

219(57-697)

8

784(169-3046)

56

<0.0005**

Lymphocyte count ≤ 0.8×109/L (no)

9

10

31

58

Duration of lymphocytopenia

5.5 (4-19)

10

5 (3-9)

58

Duration of lymphocytopenia > 5 days (no)

7

10

4

58


**..... Statistically significant with the use of a non-parametric Mann-Whitney U test; #..... Statistically significant with the use of a chi-square test or Fisher's exact test test

BMI: Body Mass Index; LDH: lactic dehydrogenase; CK: creatine kinase; AST: glutamic-oxaloacetic transaminase; ALT: glutamic alanine aminotransferase; Alb: albumin; CRP: C reactive protein.

Cui et al. BMC Infectious Diseases 2010 10:145   doi:10.1186/1471-2334-10-145

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