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Mean total blood lymphocyte counts in hemochromatosis probands with HFE C282Y homozygosity |
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| HLA |
loge lymphocyte count (cells/mm3 × 10-3 (SD)) |
lymphocyte count (cells/mm3 × 10-3 (95% CI))1 |
p value (present vs. absent)2 |
|
|
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| A*01 present |
1.012 (0.213) |
2.8 (1.8, 4.2) |
0.0362 |
| A*01 absent |
1.101 (0.184) |
3.0 (2.1, 4.3) |
|
| B*08 present |
0.975 (0.178) |
2.7 (1.9, 3.8) |
0.0048 |
| B*08 absent |
1.104 (0.189) |
3.0 (2.1, 4.4) |
|
| B*14 present |
1.160 (0.180) |
3.2 (2.2, 4.5) |
0.0317 |
| B*14 absent |
1.065 (0.192) |
2.9 (2.0, 4.2) |
|
| A*01-B*08 present |
0.943 (0.195) |
2.6 (1.8, 3.8) |
0.0026 |
| A*01-B*08 absent |
1.101 (0.185) |
3.0 (2.1, 4.3) |
|
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1Lymphocyte counts were measured at diagnosis of hemochromatosis, and are expressed as mean (95% CI) after computing antilogse of the transformed data. 2Comparisons were made using loge lymphocyte counts and student t-test (two-tail); p values < 0.05 were defined as significant. | |||
Barton et al. BMC Blood Disorders 2005 5:5 doi:10.1186/1471-2326-5-5 |
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