Table 2

Mean total blood lymphocyte counts in hemochromatosis probands with HFE C282Y homozygosity

HLA

loge lymphocyte count (cells/mm3 × 10-3 (SD))

lymphocyte count (cells/mm3 × 10-3 (95% CI))1

p value (present vs. absent)2


A*01 present

1.012 (0.213)

2.8 (1.8, 4.2)

0.0362

A*01 absent

1.101 (0.184)

3.0 (2.1, 4.3)

B*08 present

0.975 (0.178)

2.7 (1.9, 3.8)

0.0048

B*08 absent

1.104 (0.189)

3.0 (2.1, 4.4)

B*14 present

1.160 (0.180)

3.2 (2.2, 4.5)

0.0317

B*14 absent

1.065 (0.192)

2.9 (2.0, 4.2)

A*01-B*08 present

0.943 (0.195)

2.6 (1.8, 3.8)

0.0026

A*01-B*08 absent

1.101 (0.185)

3.0 (2.1, 4.3)


1Lymphocyte counts were measured at diagnosis of hemochromatosis, and are expressed as mean (95% CI) after computing antilogse of the transformed data.

2Comparisons were made using loge lymphocyte counts and student t-test (two-tail); p values < 0.05 were defined as significant.

Barton et al. BMC Blood Disorders 2005 5:5   doi:10.1186/1471-2326-5-5

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