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Iron measures in hemochromatosis probands with HFE C282Y homozygosity1 |
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| Iron measure |
Men (95% CI) [n] |
Women (95% CI) [n] |
p value |
|
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| Serum iron, μg/dL |
209 (137, 317) [81] |
193 (118, 315) [51] |
0.0523 |
| Transferrin saturation, % |
85 (59, 121) [83] |
77 (44, 133) [52] |
0.0120 |
| Serum ferritin, ng/mL |
1097 (209, 5768) [81] |
546 (84, 3535) [56] |
<0.0001 |
| Phlebotomy to achieve iron depletion, units |
29 (7, 122) [73] |
17 (4, 76) [42] |
0.0001 |
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1Serum iron, transferrin saturation, and serum ferritin levels were measured at diagnosis of hemochromatosis. Values were transformed (loge) to achieve normal distributions; comparisons were made using a student t-test (two-tail). Data displayed in the table are expressed as mean (95% CI) after computing antilogse of the transformed data; p values < 0.05 were defined as significant. | |||
Barton et al. BMC Blood Disorders 2005 5:5 doi:10.1186/1471-2326-5-5 |
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