Table 2

Features of disease severity by HbF level
Clinical features Patients with High HbF levels (≥10%) N = 80(%) Patients with low HbF levels (<10%) N = 136 (%) OR (95% CI) p value
History of dactylitis
Present 53 (66.3%) 106 (77.9%)
Absent 27 (33.7%) 30 (22.1%) 1.80 (0.97-3.53) 0.060
Age at onset of dactylitis
<1 year 37 (69.8%) 78 (73.6%)
≥ 1 year 16 (30.2%) 28 (26.4%) 1.20 (0.57-2.50) 0.617
Age at diagnosis
≤ 1 year 31 (38.8%) 54 (40%)
> 1 year 49 (61.2%) 81 (60%) 1.05 (0.59-1.86) 0.857
Hospitalisations in past year
No 40 (50%) 63 (46.3%) 1.16 (0.67-2.02) 0.602
yes 40 (50%) 73 (53.7%)
Transfusions in past year
No 62 (77.5%) 92 (67.7%) 1.65 (0.87-3.13) 0.123
Yes 18 (22.5%) 44 (32.3%)
Painful episodes in past year
No 27 (33.7%) 41 (30.1%) 1.18 (0.65-2.13) 0.583
Yes 53 (66.3%) 95 (69.9%)
History of stroke
No 76 (95%) 123 (90.4%) 2.00 (0.63-6.43) 0.231
Yes 4 (5%) 13 (9.6%)

Mpalampa et al.

Mpalampa et al. BMC Blood Disorders 2012 12:11   doi:10.1186/1471-2326-12-11

Open Data