Table 3

Association between Inappropriate Medication Use and Risk of Fall

≤ 1 fall

≥ 2 falls

Medication n (%)

(N = 4961)

(N = 1382)

RR (95% CI)

crude P-value

RR (95% CI)*

P-value*


Inappropriate medication, full list

1500 (30.2)

504 (36.5)

Inappropriate medication, excluding cerebral vasodilators

924 (18.6)

315 (22.8)

1.27 (1.12–1.43)

<.001

1.05 (0.92–1.20)

.47

Long-acting benzodiazepines

351 (7.1)

144 (10.4)

1.46 (1.23–1.74)

<.001

1.20 (1.00–1.43)

.048

Inappropriate psychotropic drugs

108 (2.2)

47 (3.4)

1.60 (1.20–2.14)

.002

1.31 (0.97–1.76)

.08

Inappropriate medication with anticholinergic properties

223 (4.5)

92 (6.7)

1.50 (1.21–1.85)

<.001

1.18 (0.96–1.47)

.13

Short- or intermediate-half-life benzodiazepines

568 (11.5)

206 (14.9)

1.31 (1.13–1.51)

<.001

0.99 (0.85–1.16)

.89


* Adjusted for age, sex, study centre, body mass index, diurnal drowsiness, number of drugs (excluding inappropriate medication), cognitive functioning, depressive symptoms and impaired mobility.

Berdot et al. BMC Geriatrics 2009 9:30   doi:10.1186/1471-2318-9-30

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