Table 2

The participants’ characteristics and comparisons between participants with and without B6 deficiency
Variable All participants n=61 Participants with p-PLP deficiency n=30 Participants with normal p-PLP n=31 p-value
Females 39 (63.9%) 20 (66.7%) 19 (61.3%) 0.667
Age (years) 85.3 (6.8) 87.2 (6.1) 83.5 (7.0) 0.032
Able to give informed consent 12 (19.7%) 5 (16.7%) 7 (22.6%) 0.607
Reside in dementia units 24 (39%) 10 (33%) 14 (45%) 0.351
Body mass index (kg/m2) (n=54) 25.7 (4.5) 25.2 (4.7) 26.1 (4.3) 0.467
p-PLP (nmol/L) 20.7 (<4.0-175.8)
Dietary vit. B6 (mg/day) females (n=38) 1.18 (0.31) 1.13 (0.28) 1.22 (0.34) 0.353
Dietary vit. B6 (mg/day), males (n=22) 1.60 (0.30) 1.53 (0.35) 1.66 (0.26) 0.332
MNA-score (n=52) 22.5 (11–27) 21.5 (11–27) 22.5 (13.5-26.5) 0.172
Dietary grain products (items/day) 11.6 (3.7) 11.6 (4.6) 11.6 (2.8) 0.984
Dietary fibre (g/day) 18.4 (6.6) 18.6 (8.1) 18.2 (4.8) 0.791
Steps per day (n=54) 200 (0–5000) 100 (0–1500) 500 (0–5000) 0.016
Katz’ ADL-index1 (n=60) 4 (0–6) 4 (0–6) 3 (0–6) 0.127
ALAT below reference value (< 10 U/L) 14 (23.0%) 11 (36.7%) 3 (9.7%) 0.014
Albumin (g/L) 39.1 (3.6) 38.0 (3.9) 40.1 (2.9) 0.022
Homocysteine (μmol/L) 18.6 (10.5) 21.5 (11.6) 15.8 (8.5) 0.032
Glomerular filtration rate2 (mL/min) (n=56) 56.6 (19.9) 55.4 (22.2) 57.7 (18.0) 0.660
Number of drugs used 6 (1–13) 5 (1–13) 6 (1–13) 0.372
Polypharmacy (> 3 drugs) 49 (80.3%) 21 (70.0%) 28 (90.3%) 0.052
Use of vit. B6 supplements (ATC A11) 14 (23.0%) 0 (0.0%) 14 (45.2%) <0.001
Use of sedatives/ hypnotics (ATC N05C) 14 (23.0%) 2 (6.7%) 12 (38.7%) 0.003
Use of SSRI (ATC N06AB) 23 (37.7%) 7 (23.3%) 16 (51.6%) 0.023
Use of anti-dementia drugs (ATC N06D) 16 (26.2%) 4 (13.3%) 12 (38.7%) 0.025

1 Score 0–6. Low score indicates independence in ADL.

2 Estimated by the Cockroft-Gault formula.

The results are given as no. (percent), mean (SD), and median (range). p-values indicate the difference between the groups with and without B6 deficiency. n=61 if not specified.

Kjeldby et al.

Kjeldby et al. BMC Geriatrics 2013 13:13   doi:10.1186/1471-2318-13-13

Open Data