Table 3

Multivariate-adjusted prevalence ratios for factors associated with restless legs syndrome* in the Health and Retirement Study 2002 survey (N = 1008)
Restless Leg Symptoms Predictor Multivariate Adjusted Model
PR 95% CI p
Age (reference: 50–64 years)
 Age 65–79 years 0.45 (0.28, 0.72) <0.001
 Age 80 or older 0.52 (0.25, 1.07) 0.07
Gender (reference: Male) 1.50 (0.93, 2.40) 0.10
Income (reference: Lowest Quartile)
2nd quartile 1.37 (0.83, 2.27) 0.22
3rd quartile 0.82 (0.46, 1.46) 0.51
4th quartile 1.54 (0.85, 2.81) 0.16
Current drinking status (reference: None) 0.59 (0.37, 0.92) 0.02
Body Mass Index (reference: BMI < 25.0)
BMI 25.0 – 29.9 1.77 (1.05, 2.99) 0.03
BMI 30 or greater 1.40 (0.80, 2.46) 0.24
Pain category (reference: None)
Mild to moderate 2.67 (1.47, 4.84) 0.001
Severe 3.44 (2.00, 5.93) <0.001
Number of chronic medications used (reference: None)
1 chronic medication 1.14 (0.57, 2.26) 0.71
2 chronic medications 1.32 (0.70, 2.46) 0.39
3 or more chronic medications 2.54 (1.26, 5.12) 0.009
Out of pocket medical expenses (reference: Highest Quartile)
2nd quartile 1.65 (0.88, 3.09) 0.12
3rd quartile 1.33 (0.69, 2.57) 0.40
4th quartile 2.12 (1.17, 3.86) 0.01
Frequency of doctor visits in last 2 years (reference: 0–3 visits)
4-7 visits 0.89 (0.43, 1.82) 0.74
8-11 visits 0.82 (0.46, 1.46) 0.50
12 or more visits 0.49 (0.27, 0.90) 0.02
Health limits ability to work 2.91 (1.75, 4.85) <0.001
Falls in the last 2 years (reference: None)
Fell once 1.33 (0.73, 2.40) 0.35
Fell 2 or more times 2.63 (1.49, 4.66) <0.001
Associated sleep problems
Problems with early waking 1.69 (1.09, 2.62) 0.02
Problems with frequent waking 1.55 (1.00, 2.41) 0.05

Abbreviations: PR = prevalence ratio; CI = confidence interval; BMI = Body Mass Index.

* Restless Legs symptoms defined as unpleasant or restless sensations in the legs at least once per week, and reporting “restless, fidgety, or unable to sit still” feelings at rest and the need to “move, rub, or stretch legs” (n = 104).

† Final multivariate model reflecting automated variable forward selection with improvements to Akaike Information Criterion statistic.

Cirillo and Wallace

Cirillo and Wallace BMC Geriatrics 2012 12:39   doi:10.1186/1471-2318-12-39

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