Table 2

Dosage of UTI prophylactic agents used in 1473 nursing home residents; Last columns: Norwegian guidelines on recommended UTI prophylactic treatments in nursing homes.

Dosage of UTI prophylactic agents used in 1473 nursing home residents

Norwegian guidelines: recommended UTI prophylaxis in nursing homes


Agents used

Mean (SD)

Dosage range

Dosage

Comments


Methenamine

1.87 g (0.47)

1 - 2 g daily

1 g twice daily

Low grade documentation****

Vitamin C

490 mg (370)

60 - 2000 mg daily

-

Not recommended

Estrogens

-

0.5 - 2 g daily*

0.5 - 1.5 mg weekly**

-

Vaginal estrogens can be tried in recurrent UTIs

Cranberry

-

1 - 2 capsules daily***

-

Low grade documentation****

Trimethoprim

110 mg (26)

100 - 160 mg daily

100 mg daily

Consider local resistance pattern

Nitrofurantoin

70 mg (35)

50 - 150 mg daily

50 mg daily

Less effective with low or intermediate eGFR*****, pulmonal and kidney function must be assessed if long term treatment


* oral daily doses, ** vaginal weekly doses estriol (50 - 52 μg estradiol weekly), *** 2 residents received 4 ml mixture or 0.5 drinking glass of cranberry juice daily

**** Evidence grading system as commonly used in clinical practice Guidelines

***** Estimated glomerular filtration rate

Bergman et al. BMC Geriatrics 2011 11:69   doi:10.1186/1471-2318-11-69

Open Data