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Articles
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BMC Biology 2012, 10:45Evolution of the vertebrate retina
A string of remarkable similarities between dopamine-synthesizing cells that modulate the photic responses of ascidian larvae, and amacrine cells of the vertebrate retina, suggests a common evolutionary origin from ancestral cells in the photoreceptive field of the anterior neural tube of chordates.
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BMC Medicine 2012, 10:52Challenges in biomarker tests
Translation of tissue specific markers into clinically useful marker-based tests for diagnosis and prognosis faces many statistical challenges; Lisa McShane discusses these, noting that statistical evaluation is essential in test development.
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BMC Medicine 2012, 10:51Biomarker reporting: REMARK guidelines
Altman et al. address the lack of consistency and clarity in reporting of prognostic tumor markers by elaborating the Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK) checklist, providing a useful resource for researchers.
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Genome Medicine 2012, 4:47H3K4me3 represses non-CpG island genes
Epigenetic mark H3K4me3 is demonstrated to protect both CpG-island and non-CpG island start sites in colon cancer from DNA methylation, suggesting similar mechanisms in both cases.
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Genome Medicine 2012, 4:48Evaluating uncertain gene variants in the clinic
A new method compares computer-based predictions of missense variants of uncertain significance and provides a visualization tool to aid clinical decision making.
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Affective disorders: mind, body and society in the limelight
In conjunction with Mental Health Awareness Week (21st-27th May) BMC Medicine wants to highlight mood disorders such as unipolar and bipolar depression. To find out more please visit our blog.
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Introducing the BioMed Central author academy
Edanz have created the BioMed Central Author Academy, an online learning resource for authors on writing and publishing scientific journals, which aims to work with authors to improve the quality of manuscripts sent for peer-review.
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Challenges in Malaria Research announces program
The program has been announced for the 2nd biennial Challenges in Malaria Research conference, which takes place in Basel, Switzerland from 10th-12th October 2012. Visit the conference website for further information.
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Three days to go until the Metabolism, Diet and Disease conference
The Metabolism, Diet and Disease 2012 conference, hosted by BioMed Central in association with its journals BMC Biology and BMC Medicine, which takes place in Washington DC, USA from 29-31 May 2012.
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