Table 2 |
|||||
|
Distribution of cagA and vacA alleles in patients |
|||||
|
Diagnosis in patients n = 224 |
|||||
|
|
|||||
|
Virulence marker |
Non ulcer dyspepsia n = 120 |
Gastric ulcer n = 32 |
Gastric carcinoma n = 40 |
Duodenal ulcer n = 32 |
P value* |
|
|
|||||
|
CagA |
|||||
|
Positive |
51 (42) |
20(62) |
31(77) |
23(72) |
<0.001 |
|
Negative |
69 (58) |
12(38) |
9(23) |
9(28) |
|
|
VacAs1a |
|||||
|
Positive |
79 (66) |
25(78) |
31(77) |
19(59) |
0.211 |
|
Negative |
41 (34) |
7(22) |
9(23) |
13(41) |
|
|
VacAs1b |
|||||
|
Positive |
30 (25) |
12 (37) |
17 (42) |
13 (41) |
0.100 |
|
Negative |
90 (75) |
20(63) |
23(58) |
19 (59) |
|
|
VacAm1 |
|||||
|
Positive |
50 (42) |
27(84) |
29(72) |
29(91) |
<0.001 |
|
Negative |
70 (58) |
5(16) |
11(28) |
3(9) |
|
|
VacAm2 |
|||||
|
Positive |
74 (62) |
15(47) |
15(37) |
12(37) |
<0.01 |
|
Negative |
46 (38) |
17(53) |
25(63) |
20(63) |
|
|
VacAs1am1 |
|||||
|
Positive |
38 (32%) |
23(72) |
23(56) |
17(53) |
<0.001 |
|
Negative |
82 (68%) |
9(28) |
17(44) |
15(47) |
|
|
VacAs1bm1 |
|||||
|
Positive |
13 (11) |
9(28) |
11(28) |
12(38) |
<0.001 |
|
Negative |
107 (89) |
23(72) |
29(82) |
20(62) |
|
|
CagA s1am1 |
|||||
|
Positive |
22 (18) |
11(34) |
22(55) |
11(34) |
<0.001 |
|
Negative |
98(82) |
21(66) |
18(45) |
21(66) |
|
|
CagA s1bm1 |
|||||
|
Positive |
19 (16) |
11(34) |
7(18) |
5(16) |
0.01 |
|
Negative |
101 (84) |
21(66) |
33 (82) |
27(84) |
|
|
vacAi |
|||||
|
i1 and i2 positive |
4(3) |
0 |
2(5) |
0 |
< 0.001 |
|
i1 and i2 negative |
2(2) |
2(6) |
1(3) |
0 |
|
|
i1 positive |
5(4) |
27(85) |
33(82) |
27(84) |
|
|
i2 positive |
109(91) |
3(9) |
4(10) |
5(16) |
|
|
|
|||||
|
* Differences in proportion were assessed by using Pearson Chi square, Fisher exact or likelihood ratio test where appropriate. |
|||||
|
Yakoob et al. BMC Gastroenterology 2009 9:87 doi:10.1186/1471-230X-9-87 |
|||||
