Table 5

Genotype frequencies for PTPN11 rs2301756 polymorphism, age-sex adjusted odds ratios (ORs) and 95% confidence intervals (CIs) of gastric cancer relative to H. pylori infected subjects without gastric atrophy (HP-infected without atrophy).

Genotype

HP infected without atrophy n = 442

Gastric cancer n = 583

OR

95% CI

P value

G/G

293 (66.3%)

396 (67.9%)

1

Reference

-

G/A

135 (30.5%)

174 (29.8%)

0.97

0.74–1.28

0.839

A/A

14 (3.2%)

13 (2.2%)

0.71

0.33–1.53

0.381

G/A+A/A

149 (33.7%)

187 (32.1%)

0.95

0.73–1.23

0.689

G

721 (81.6%)

966 (82.8%)

1

Reference

-

A

163 (18.4%)

200 (17.2%)

0.92

0.72–1.16

0.243

^aOR for each genotype was calculated by age and sex adjusted logistic regression model, and a crude OR was calculated for each allele.

Hishida et al. BMC Gastroenterology 2009 9:51   doi:10.1186/1471-230X-9-51