Table 2

Prevalence and Incidence of Celiac Disease (CD) and Seropositivity for IgA Class Tissue Transglutaminase (tTGA) and Endomysial (EmA) Antibodies in Patients Aged Over 55 Years.

Year, total population

Procedure

Number clinically detected

tTGA positive in screening

EmA positive in screening

Biopsy-proven cases in screening

Overall frequency of biopsy proven CD

Patients with CD and tTGA seropositive individuals

2002, 2815

Serum sampling

2004, 2815

Recording of detected CD. First serologic analysis

25

48

43

35

60

69^a

2005, 2216

Recording of detected CD. Second serologic screening

1

6

4

5^b

6

7

Overall prevalence, N = 2815

0.92% (26/2815)

1.92%

(54/2815)

1.70% (47/2815)

1.42%

(40/2815)

2.34%

(66/2815)

2.70%

(76/2815)

95% confidence intervals

0.57–1.27%

1.41–2.43%

1.22–2.18%

0.98–1.86%

1.78–2.90%

2.10–3.30%

^a Four seropositive were found to have celiac disease between 2002–2004

^bThe incidence of celiac disease 2002–2005 was 0.23% (5/2216)

Vilppula et al. BMC Gastroenterology 2009 9:49   doi:10.1186/1471-230X-9-49