Table 1

Prevalence of virulence-associated genes in A+B1 (commensal) and B2+D (virulent) E. coli clones isolated from active and non-active coeliac disease patients and healthy children

Virulence factor (gene)

Virulent B2 + D clones (%)*

Commensal A + B1 clones (%)*


Active coeliac

(n = 23)

Non-active coeliac

(n = 23)

Healthy

(n = 21)

Active coeliac

(n = 17)

Non-active coeliac

(n = 19)

Healthy

(n = 19)


Type 1 fimbriae

(fim A)

18 (78)a

18 (78)a

10 (48)a

11 (65)a

14 (82)a

16 (84)a

S fimbriae

(sfaD/E)

8 (35)a

9 (39)a

8 (38)a

0a

6 (35) b

1 (5) a

P fimbriae

(papC)

5 (22)a

9 (39)a

0b

0a

0a

4 (21)a

Dr haemagglutinin

(draA)

0a

0a

0a

0a

0a

0a

Haemolysin

(hlyA)

5 (22)ab

9 (39)b

1 (5)a

0a

1 (6)a

4 (21)a

K1

(neuB)

8 (35)a

5 (22)a

5 (24)a

0a

10 (59) b

8 (42)b

K5

(KfiC)

6 (26)a

0b

2 (10)ab

0a

0a

1 (5)a

Aerobactin

(iutA)

4 (17)a

4 (17)a

7 (33)a

1 (6)a

6 (35)ab

12 (63) b


*Different letters (a to b) in the same row and within the same phylogenetic group (virulent B2+D or commensal A+B1) indicate significant differences in the gene-carriage.

S├ínchez et al. BMC Gastroenterology 2008 8:50   doi:10.1186/1471-230X-8-50

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