Table 1

Transformation of T51B cells by MNNG and FAC1.

MNNG

FAC

Number of colonies per 25,000 cells


0

0

0.0 (+/- 0.0)

0.5

0

1.3 (+/- 0.8)

0

20 μM

1.5 (+/- 0.5)

0.5

20 μM

4.3 (+/- 1.0)

0

50 μM

1.8* (+/- 0.2)

0.5

50 μM

17.5 (+/- 3.3)

0

200 μM

1.8 (+/- 1.4)

0.5

200 μM

21.5* (+/- 2.1)

0

500 μM

3.0 (+/- 1.4)

0.5

500 μM

5.3 (+/- 1.3)


1 Cells exposed or not to 0.5 μg/ml MNNG were cultured in FAC for 12 weeks (6 passages) prior to soft agar assay: means of n = 4 dishes (+/- s.e.m); *p < 0.01 compared to untreated cells.

Messner and Kowdley BMC Gastroenterology 2008 8:2   doi:10.1186/1471-230X-8-2

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