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Cut-points, Sensitivities, Specificities and ROC Areas for Pathologic Integrated Esophageal Acidity and Time Esophageal pH < 4. |
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| Period |
Integrated Acidity (mmol.hr/L) |
Time pH < 4(%) |
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|
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| 24-hour (900–900) |
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| Cut-point |
8.1 |
4.3 |
| Sensitivity (%) |
72 |
89 |
| Specificity (%) |
88 |
81 |
| ROC Area |
0.86 [0.77,0.94] |
0.90 [0.84, 0.97] |
| Postprandial (900–2200) |
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| Cut-point |
1.85 |
6.8 |
| Sensitivity (%) |
92 |
85 |
| Specificity (%) |
62 |
85 |
| ROC Area |
0.82 [0.72, 0.91] |
0.88 [0.80, 0.95] |
| Nocturnal (2200–900) |
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| Cut-point |
1.3 |
2.1 |
| Sensitivity (%) |
79 |
81 |
| Specificity (%) |
77 |
85 |
| ROC Area |
0.79 [0.69, .90] |
0.84 [0.74, .92] |
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Results are from 26 normal and 57 GERD subjects. Values in brackets for ROC area are the 95 % confidence intervals. | ||
Gerson et al. BMC Gastroenterology 2008 8:15 doi:10.1186/1471-230X-8-15 |
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