Figure 2.

Impaired resolution of centrilobular injury in mice lacking receptor-free uPA. Histological liver sections 2 days after CCl4 show similar features of centrilobular necrosis (arrows) in mice of all genotypes. While livers from wild type (WT), uPAR°, and uPAR°/tPA° show resolution of the centrilobular injury by day 7, uPA° livers continue to display the injury at 7 and 14 days after CCl4 despite the presence of uPAR (Magnification 200×)

Shanmukhappa et al. BMC Gastroenterology 2006 6:40   doi:10.1186/1471-230X-6-40
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