Table 2

Univariate analysis of risk of change of disease behaviour in patients with B1 disease at diagnosis

Patients without change of disease behaviour (N = 42)

Patients with change of disease behaviour (N = 38)

P§


Males

26 (61.9%)

20 (52.6%)

0.180

Months to diagnosis

49.2 ± 43.5

39.6 ± 41.2

NS

A1

29 (69%)

31 (81.5%)

0.147

Positive family history

4 (9.5%)

6 (15.7%)

NS

Location of disease

L1

3 (11.9%)

9 (23.6%)

0.005

L2

20 (47.6%)

5 (13.1%)

0.006

L3

15 (35.7 %)

19 (50%)

NS

L4

4 (9.5%)

5 (13.1%)

NS

Current smoking

13 (30.9%)

28 (73.6%)

0.001

Continuous course

4 (9.5%)

13 (34.2%)

0.016

Immunosuppressives

11 (26.1%)

9 (23.6%)*

NS

Surgery at diagnosis

1 (2.3%)

1 (2.6%)

NS


Values are given as mean ± SD or number of patients; Values in parentheses are percentages; N, number; A1, age at diagnosis ≤ 40 years; L1, ileal location; L2, colonic location; L3, ileo-colonic location; L4, disease of the upper gastro-intestinal tract; *Data collected until change of disease behavior; §P values from survival analysis using log-rank test; Surgery at diagnosis refers to bowel resections; Variables having a p value between 0.51 and 0.2, although insignificant, were included in the regression analysis to avoid confounding effects;

Chatzicostas et al. BMC Gastroenterology 2006 6:21   doi:10.1186/1471-230X-6-21

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