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Parameters of the endotoxin dose-response curves for food intake over time. Results of the fitted model examining the effect of various doses of endotoxin on nocturnal food intake extended to include the four nights after LPS injection. |
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| Parameter |
Estimate |
95% Confidence Interval |
|
|
||
| A – minimum, grams |
0.13 |
(0.05, 0.21) |
| B – baseline, grams |
3.50 |
(3.61, 3.72) |
| Dm(1) – median effect dose for the first night, mg/kg |
0.010 |
(0.007, 0.012) |
| c – multiplier of the median effect dose for each additional night |
11.00 |
(8.62, 14.04) |
| sB – standard deviation of B, g |
0.27 |
(0.18, 0.39) |
| sD – standard deviation of logDm(1), g |
0.47 |
(0.33, 0.66) |
| s – residual standard deviation, grams |
0.23 |
(0.20, 0.26) |
Firpo et al. BMC Gastroenterology 2005 5:18 doi:10.1186/1471-230X-5-18 |
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