Table 1 |
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|
The vacA, iceA, cagA and cagE status of H. pylori strains and clinical outcome |
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|
Clinical Outcome |
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|
|
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|
Genotype |
PUD n (%) |
NUD n (%) |
GERD n (%) |
Total n (%) |
|
|
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|
vacA |
||||
|
s1 |
57 (78)* |
25 (54) |
4 (21) |
86 (62) |
|
s2 |
16 (22) |
21 (46) |
15 (79)** |
52 (38) |
|
m1 |
27 (37) |
11 (24) |
3 (16) |
41 (30) |
|
m2 |
46 (63) |
35 (76) |
16 (84) |
97 (70) |
|
s1m1 |
27 (37) |
11 (24) |
3 (16) |
41 (30) |
|
s1m2 |
30 (41)* |
14 (30) |
1 (5) |
45 (32) |
|
s2m2 |
16 (22) |
21 (46) |
15 (79)** |
52 (38) |
|
iceA |
||||
|
iceA1 |
12 (16) |
6 (13) |
3 (16) |
21 (15) |
|
iceA2 |
55 (75) |
32 (70) |
15 (79) |
102 (74) |
|
iceA - |
6 (9) |
8 (17) |
1 (5) |
15 (11) |
|
cagA |
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|
cagA + |
55 (75)* |
25 (54) |
9 (47) |
89 (65) |
|
cagA - |
18 (25) |
21 (46) |
10 (53) |
49 (35) |
|
cagE |
||||
|
cagE + |
60 (82) |
39 (85) |
17 (90) |
116 (84) |
|
cagE - |
13 (13) |
6 (15) |
2 (10) |
22 (16) |
|
|
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|
* vacA s1 (χ2 = 14.3; p = 0.0002) s1m2 (χ2 = 15.67; p = 0.0004) cagA (χ2 = 7.954; p = 0.0048). ** s2m2 (χ2 = 16.89; p = 0.0002) |
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|
Godoy et al. BMC Gastroenterology 2003 3:20 doi:10.1186/1471-230X-3-20 |
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