Table 2

Analysis of gene expression in the fundus of wild type and W/WV mice

Gene Name
W/WV/wildtype ratio(a)
Accession No.
Subcellular location(b)
Cytoband(c)

EST
2.5
AA185701


EST
2.5
AA166336


EST
2.4
AA021806


MCM7: DNA Replication Licensing Factor
2.4
Q61881
nucleus
7q21.3-q22.1
p160 ROCK2: Rho-Associated Protein Kinase
2.3
U58513
cytoskeleton
2p24
EST
2.3
W18585


EST
2.3
AA403748


BST1/BP3: ADP-Ribosyl Cyclase 2 Precursor
2.0
Q64277
membrane
4p15
EST
2.0
AA024250


RBP2: retinol binding protein 2, cellular
2.0
Q08652
cytoplasm
3q23
EST
2.0
W46016


BP1/6C3: Glutamyl Aminopeptitase
-2.1
S30398
membrane
16
EST
-2.2
AI552444


EST
-2.3
AA108876


EST
-2.4
AA049294


EST
-2.4
AA254777


RHAMM: Hyaluronan-Mediated Motility Receptor
-2.5
AF031932
membrane
5q33.2-qter
EST
-2.5
AA002293


EST
-3.4
AI595081


CPO: Coproporphyrinogen Oxidase
-3.6
D16333
mitochondria
3q12
EST
-3.9
AA000304



(a) Balanced differential expression for control wild type mice vs W/W V mutant mice. Values that were decreased or increased by > 2-fold or greater in both two independent experiments were considered significant and the mean values were calculated. All of the results were confirmed with semi-quantitative RT-PCR using fundic tissues from six wild type and six W/WV mutant mice. (b) Subcellular location determined by the SOURCE program http://source.stanford.edu. (c) Human chromosomal localization of the gene.

Daigo et al. BMC Gastroenterology 2003 3:14   doi:10.1186/1471-230X-3-14