Table 1 |
||||
|
The ulcerogenic and intestinal permeability (51Cr-EDTA excretion) effect of DMSO (Control), indomethacin, DAHP pretreated indomethacin and nabumetone gavaged rat small intestine. |
||||
|
Group |
Treatment |
Pointed ulcers |
Longitudinal ulcers |
% Excretion of 51Cr-EDTA in Urine |
|
|
||||
|
1 |
Control(DMSO) |
0 |
0 |
2.3 ± 1.2 |
|
2 |
Indomethacin |
55 ± 10 |
15 ± 9 |
* 10.5 ± 2.5 |
|
3 |
DAHP pretreated indomethacin |
0 |
0 |
* 11.5 ± 0.8 |
|
4 |
Nabumetone |
0 |
0 |
2.7 ± 1.5 |
|
|
||||
|
* P < 0.01 |
||||
|
Somasundaram et al. BMC Gastroenterology 2002 2:8 doi:10.1186/1471-230X-2-8 |
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