Table 4

Cox multivariate analysis separately shown for patients belonging to the two groups of treatment1
Surgery alone 5-Fu therapy
HR (p) HR (p)
Clinical-pathological features Age 0.66 (0.6) 3.43 (0.2)
Sex 0.99 (1.0) 1.34 (0.8)
Tumour location 2.09 (0.5) 1.36 (0.7)
Tumour grade 0.71 (0.7) 1.99 (0.7)
Depth of tumour invasion 5.22 (0.2) 1.26 (0.9)
Lymphovascular invasion 0.50 (0.4) 0.27 (0.2)
Large veins invasion 2.14 (0.4) 0.40 (0.3)
Tumour inflammatory response 1.30 (0.6) 0.53 (0.1)
Tumour border configuration 4.91 (0.2) 2.18 (0.6)
Molecular parameters MMR system 0.15 (0.2) 37.85 (0.04)
CIMP 0.67 (0.6) 0.17 (0.05)
TS by mRNA 6.08 (0.04) 0.54 (0.2)
TS by IHC 0.35 (0.1) 2.03 (0.4)
TP53 0.71 (0.7) 0.63 (0.6)
CTNNB1activation grades 0.35 (0.1) 1.60 (0.5)
BRAF c.1799 T > A 2.67 (0.3) 2.99 (0.3)

1Results of Cox multivariate analysis here reported are referred to DFS (disease free survival). Significant or borderline p values are bolded.

Donada et al.

Donada et al. BMC Gastroenterology 2013 13:36   doi:10.1186/1471-230X-13-36

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