Table 1

Cohort baseline at menopause diagnosis according to use or non-use of hormone
Characteristics Oestrogen Users N = 7678) Tibolone Users N = 1539 Combined Hormone users N = 9137 Progestogen Users N = 3747 Non-users N = 29081 (%)
Age (y) 40 to 49 2987 (39%) 275 (18%) 3941 (43%) 2212 (59%) 9795 (34%)
50 to 59 3229 (42%) 902 (59%) 4464 (49%) 1348 (36%) 13189 (45%)
60 to 70 1462 (19%) 362 (24%) 732 (8%) 187 (5%) 6097 (21%)
Mean (SD) 52.6 (7.23) 55.1 (6.16) 50.9 (5.54) 49.1 (5.44) 53.4 (7.24)
Alcohol user1 Non-user 583 (16%) 104 (14%) 617 (14%) 279 (16%) 2243 (17%)
User 3097 (83%) 615 (85%) 3840 (85%) 1437 (83%) 10386 (81%)
Ex-user 69 (2%) 7 (1%) 57 (1%) 20 (1%) 197 (2%)
Smoker2 Non-user 2526 (53%) 501 (54%) 2966 (52%) 1208 (54%) 9719 (59%)
User 1452 (30%) 279 (30%) 1817 (32%) 720 (32%) 4010 (24%)
Ex-user 800 (17%) 149 (16%) 955 (17%) 317 (14%) 2766 (17%)
BMI3 Underweight 76 (2%) 13 (1%) 86 (2%) 24 (1%) 222 (1%)
Normal 1928 (41%) 374 (40%) 2524 (44%) 833 (39%) 5771 (37%)
Overweight 1606 (34%) 338 (36%) 1943 (34%) 627 (30%) 5038 (32%)
Obese 1004 (21%) 194 (21%) 1034 (18%) 530 (25%) 3812 (25%)
Morbidly Obese 121 (3%) 25 (3%) 122 (2%) 104 (5%) 702 (5%)
Mean (SD) 26.9 (5.47) 27.1 (5.80) 26.4 (5.17) 27.7 (6.39) 27.7 (6.11)
Practice IMD4 0 1759 (23%) 311 (20%) 1988 (22%) 832 (22%) 6112 (21%)
1 1252 (16%) 248 (16%) 1609 (18%) 702 (19%) 5287 (16%)
2 1578 (21%) 255 (17%) 1804 (20%) 764 (20%) 5743 (20%)
3 1453 (19%) 344 (22%) 1751 (19%) 731 (20%) 5757 (20%)
4 1636 (21%) 381 (25%) 1985 (22%) 718 (19%) 6182 (21%)
Hysterectomy 3470 (45%) 165 (11%) 462 (5%) 472 (13%) 3229 (11%)
NSAID use 4191 (55%) 879 (57%) 4750 (52%) 2242 (60%) 13993 (48%)
Bisphophonates 188 (2%) 57 (4%) 192 (2%) 53 (2%) 827 (3%)
Calcium supplements 419 (5%) 118 (8%) 477 (5%) 113 (3%) 1707 (6%)
GORD symptoms5 1915 (25%) 387 (25%) 2031 (22%) 859 (23%) 6689 (23%)
PPI use5 564 (7%) 88 (6%) 555 (6%) 239 (6%) 1947 (7%)

154% of patients had missing data.

241% of patients had missing data.

343% of patients had missing data.

4Index of Multiple Deprivation (IMD) based on practice post-code. Quintile 0 is the least deprived, quintile 4 is the most deprived.

5Prior to menopause.

Close et al.

Close et al. BMC Gastroenterology 2012 12:56   doi:10.1186/1471-230X-12-56

Open Data